 
 
 
 
 
 
 
  
As a starting point, the principle of this manipulation technique is tested with the simplest setup. A single straight conducting line with two contact pads at both ends is patterned with optical lithography. Above the conducting line, a drop of water with magnetic markers is placed. A current through the line creates a magnetic gradient field, that magnetises the superparamagnetic markers, aligns them to the magnetic field and pulls the markers to the conducting line. Figure 3.6 shows 5 selected images of the video of this simple experiment.
| 
[0sec] ![\includegraphics[width=.3\textwidth]{Bilder/Leiter1}](img149.png) [10sec] ![\includegraphics[width=.3\textwidth]{Bilder/Leiter2}](img150.png) [20sec] ![\includegraphics[width=.3\textwidth]{Bilder/Leiter3}](img151.png) [30sec] ![\includegraphics[width=.3\textwidth]{Bilder/Leiter4}](img152.png) [33sec] ![\includegraphics[width=.3\textwidth]{Bilder/Leiter5}](img153.png)  | 
A constant current of 5mA is already enough to attract a magnetic
marker that is about 33 m away. Without the magnetic field, the marker
just follows the brownian motion [78], but with the
magnetic gradient field it slowly moves towards the conducting line. The
marker accelerates towards the conducting line until it reaches the
local field maxima on top of the line. Before it reaches the conducting
line, the maximum velocity of the bead is about 6
m away. Without the magnetic field, the marker
just follows the brownian motion [78], but with the
magnetic gradient field it slowly moves towards the conducting line. The
marker accelerates towards the conducting line until it reaches the
local field maxima on top of the line. Before it reaches the conducting
line, the maximum velocity of the bead is about 6 m/sec.
m/sec.
In order to describe the forces that act on the magnetic marker, the
friction of the marker in the fluid (STOKES' law)
has to be subtracted from the magnetic force (see equation
1.10 on page ![[*]](crossref.png) ):
):
 , a viscosity
, a viscosity
 of the water drop and an actual velocity
 of the water drop and an actual velocity  of the marker.
Using equation 3.1, the maximum possible velocity
can be calculated, when
 of the marker.
Using equation 3.1, the maximum possible velocity
can be calculated, when 
 .
With a maximum current of
.
With a maximum current of  mA, a magnetic moment of
mA, a magnetic moment of
 fAm
fAm of the particle (see table 1.1), a
distance
 of the particle (see table 1.1), a
distance 
 m, a radius of the marker
m, a radius of the marker 
 m and a viscosity
for water of
m and a viscosity
for water of  mPasec at room temperature, the maximum
possible velocity is:
mPasec at room temperature, the maximum
possible velocity is:
This initial experiment proves that in principle the manipulation works well. Several more examples for particle manipulation are following.
 
 
 
 
 
 
